In the symptomatic treatment of many neuromuscular diseases (such as in the case of excessive, abnormal muscle tone, spasticity, torticollis, clubfoot, cerebral palsy or multiple sclerosis) injection of botulinum neurotoxin (BoNT) is used. BoNT lowers muscle tension. In order to achieve sustained improvement, in many cases repeated injections and high doses of BoNT must be […]
